Effect of inosine on red cell preservation.

to be the same. However, since some samples of blood stored in ACDI in the present study did give satisfactory survival results at 35 and 42 days, it has been suggested that red cells of different individuals may vary in their ability to withstand prolonged storage. It should be noted that the purine nucleosides are metabolized to uric acid. While in healthy volunteers the transfusion of450 ml of blood was without apparent toxicity, the effect of multiple transfusions is not known. The possible toxicity of these purine compounds is under investigation at this time.